Russia launched a large-scale missile and drone attack against Ukraine overnight Friday into Saturday, mainly targeting Kyiv and its surrounding region.

Ukrainian authorities said air defenses intercepted or disabled 149 of 172 drones and four missiles.

Three people, including a child, were injured. A residential building, a kindergarten and energy infrastructure were damaged, including substations transmitting electricity from two nuclear power plants to central Ukraine.

Ukraine’s General Staff separately announced a Neptune missile strike on a military factory in Russia’s Oryol region.

The escalation comes ahead of planned US-mediated talks in Abu Dhabi concerning Ukraine.